DIRECT
COMPRESSION - LOW DOSAGE - IMMEDIATE
RELEASE - FAST DISSOLVING TABLETS
Meet all specifications of the
USP/NF, Eur. Ph. and JP.
This particular
excipient was developed
in the framework of
NPTAB®
Technology. These
particles are prepared
by a spraying process,
allowing to produce
pellets with defined
technical properties.
Mechanical characterization
established NPTAB®
ability to direct
compression :
·
Specific Surface
area
Surface area
: 0.15 - 0.20 m²/g
(vary with particle
size) High surface
area available for
the active coating
SEM observation of
NPTAB®
particles surface
(above)
and coated NPTAB®
particles
surface (below)
The
high surface area
permits efficient
formulations for API's
high doses.
· Flow property Due to its
spherical shape and
homogeneous distribution
size and texture,
NPTAB®
particles coated or
not exhibit free
flow properties.
Carr index < 10%
Flow time < 10 s
· Compressibility
NPTAB®
(coated with active
or not) exhibit a
very good compressibility.
NPTAB®
is a directly compressible
excipient.
· Tablets cohesion
Thanks
to the plastic behaviour
and the high specific
area of pellets,
tablets of NPTAB®
exhibit good
cohesion properties.
NPTAB®
are available in
different particles
sizes :
